sample of publications

• articles 

  • Optimizing Point Source Tracking in Awake Rat PET Imaging: A Comprehensive Study of Motion Detection and Best Correction Conditions.  Applied Sciences-Basel.  13, 12329. 2023
  • Reconstruction of multi-animal PET acquisitions with anisotropically variant PSF.  Biomedical Physics and Engineering Express.  9:1-14. 2023
  • Scintillator Geometrical Considerations for Detectors Based on Hexagonal SiPMs.  IEEE Transactions on Radiation and Plasma Medical Sciences.  7. 2023
  • Determination of the pharmacokinetics and pharmacodynamics of Isoniazid, Rifampicin, Pyrazinamide and Ethambutol in a cross-over cynomolgus macaque model of Mycobacterium tuberculosis infection.  Pharmaceutics.  14:1-21. 2022
  • Innovations in ex vivo Light Sheet Fluorescence Microscopy.  PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY.  168:37-51. 2022
  • The contribution of microfluidics to the fight against tuberculosis.  Nanotechnology Reviews.  11:40-54. 2022
  • Molecular imaging of pulmonary Tuberculosis in an Ex-Vivo Mouse Model Using Spectral Photon-Counting Computed Tomography and Micro-CT.  IEEE Access.  9:67201-67208. 2021
  • Super-iterative Image Reconstruction in PET.  IEEE Transactions on Computational Imaging.  7:248-257. 2021
  • Development of an Inverted Epifluorescence Microscope for Long-Term Monitoring of Bacteria in Multiplexed Microfluidic Devices.  SENSORS.  20:1-14. 2020
  • Real-time 3D PET image with pseudoinverse reconstruction.  Applied Sciences-Basel.  10. 2020
  • A radiological score for the assessment of tuberculosis progression: Validation in mouse models.  Tuberculosis.  121. 2020
  • Simplified statistical image reconstruction for X-ray CT with beam-hardening artifact compensation.  IEEE TRANSACTIONS ON MEDICAL IMAGING.  39:111-118. 2020
  • X-ray-based virtual slicing of TB-infected lungs.  Scientific Reports.  9:19404. 2019
  • SiPM-based PET detector module for a 4pi span scanner.  NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT.  936:18-21. 2019
  • Computed tomography-based biomarker for longitudinal assessment of disease Burden in pulmonary tuberculosis.  MOLECULAR IMAGING AND BIOLOGY.  21:19-24. 2019
  • Chemoenzymatic radiosynthesis of 2-deoxy-2-[18F]fluoro-D-trehalose ([18F]-2-FDTre): a PET radioprobe for in vivo tracing of trehalose metabolism.  Carbohydrate Research.  472:16-22. 2019
  • Applications of light-sheet microscopy in microdevices.  Frontiers in Neuroanatomy.  13:1-15. 2019
  • Surface scanning for 3D dose calculation in intraoperative electron radiation therapy.  Radiation Oncology.  13:1-12. 2018
  • Improving PET Quantification of Small Animal [Ga-68]DOTA-Labeled PET/CT Studies by Using a CT-Based Positron Range Correction.  MOLECULAR IMAGING AND BIOLOGY.  20:584-593. 2018
  • Unsupervised CT lung image segmentation of a mycobacterium tuberculosis infection model.  Scientific Reports.  8 (9802):1-10. 2018
  • Optimized CUBIC protocol for three-dimensional imaging of chicken embryos at single-cell resolution.  DEVELOPMENT.  144:2092-2097. 2017
  • 3D imaging in CUBIC-cleared mouse heart tissue: going deeper.  Biomedical Optics Express.  7. 2016
  • Experimental validation of gallium production and isotope-dependent positron range correction in PET.  NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT.  814:110-116. 2016
  • Automatic Cardiac Self-Gating of Small-Animal PET Data.  MOLECULAR IMAGING AND BIOLOGY.  18:109-116. 2016
  • Functional segmentation of dynamic PET studies: Open source implementation and validation of a leader-follower-based algorithm.  COMPUTERS IN BIOLOGY AND MEDICINE.  69:181-188. 2016
  • Tissue-Dependent and Spatially-Variant Positron Range Correction in 3D PET.  IEEE TRANSACTIONS ON MEDICAL IMAGING.  34:2394-2403. 2015
  • Improved quantification for local regions of interest in preclinical PET imaging.  PHYSICS IN MEDICINE AND BIOLOGY.  60:7127-7149. 2015
  • Investigation of different sparsity transforms for the PICCS algorithm in small-animal respiratory gated CT.  PLoS One.  10:1-18. 2015
  • Development and validation of an open source quantification tool for DSC-MRI studies.  COMPUTERS IN BIOLOGY AND MEDICINE.  58:56-62. 2015
  • Recovery and normalization of triple coincidences in PET.  MEDICAL PHYSICS.  42:1398-1410. 2015
  • Positron Emission Tomography: Current Challenges and Opportunities for Technological Advances in Clinical and Preclinical Imaging Systems.  Annual Review of Biomedical Engineering.  17:385-414. 2015
  • Comparison of Methods to Reduce Myocardial 18F-FDG Uptake in Mice: Calcium Channel Blockers versus High-Fat Diets.  PLoS One.  9:1-6. 2014
  • Application of the compressed sensing technique to self-gated cardiac cine sequences in small animals.  MAGNETIC RESONANCE IN MEDICINE.  72:369-380. 2014
  • Avances tecnológicos en imagen molecular preclínica.  Radioprotección : revista española de la Sociedad Española de Protección Radiológica.  XXI:20-25. 2014
  • Dual-exposure technique for extending the dynamic range of X-ray flat panel detectors.  PHYSICS IN MEDICINE AND BIOLOGY.  59:421-439. 2014
  • Modification of the TASMIP x-ray spectral model for the simulation of microfocus x-ray sources.  MEDICAL PHYSICS.  41. 2014
  • jClustering, an open framework for the development of 4D clustering algorithms.  PLoS One.  8:1-7. 2013
  • Positron range estimations with PeneloPET.  PHYSICS IN MEDICINE AND BIOLOGY.  58:5127-5152. 2013
  • Automatic TAC extraction from dynamic cardiac PET imaging using iterative correlation from a population template.  Computer Methods and Programs in Biomedicine.  111:308-314. 2013
  • Use of Split Bregman denoising for iterative reconstruction in fluorescence diffuse optical tomography.  JOURNAL OF BIOMEDICAL OPTICS.  18. 2013
  • Monte Carlo study of the effects of system geometry and antiscatter grids on cone-beam CT scatter distributions.  MEDICAL PHYSICS.  40. 2013
  • Improved dead-time correction for PET scanners: application to small-animal PET.  PHYSICS IN MEDICINE AND BIOLOGY.  58:2059-2072. 2013
  • MRI compatibility of position-sensitive photomultiplier depth-of-interaction PET detectors modules for in-line multimodality preclinical studies.  NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT.  702:83-87. 2013
  • Massively parallelizable list-mode reconstruction using a Monte Carlo-based elliptical Gaussian model.  MEDICAL PHYSICS.  40:1-11. 2013
  • Misalignments calibration in small-animal PET scanners based on rotating planar detectors and parallel-beam geometry.  PHYSICS IN MEDICINE AND BIOLOGY.  57:7493-7518. 2012
  • Approach to assessing myocardial perfusion in rats using static [13N]-ammonia images and a small-animal PET.  MOLECULAR IMAGING AND BIOLOGY.  14:541-545. 2012
  • NEMA NU 4-2008 comparison of preclinical PET imaging systems.  JOURNAL OF NUCLEAR MEDICINE.  53:1300-1309. 2012
  • Software architecture for multi-bed FDK-based reconstruction in X-ray CT scanners.  Computer Methods and Programs in Biomedicine.  107:218-232. 2012
  • A method for small-animal PET/CT alignment calibration.  PHYSICS IN MEDICINE AND BIOLOGY.  57:199-207. 2012
  • Waking-like brain function in embryos.  CURRENT BIOLOGY.  22:852-861. 2012
  • Accuracy of CT-based attenuation correction in PET/CT bone imaging.  PHYSICS IN MEDICINE AND BIOLOGY.  57:2477-2490. 2012
  • Influence of absorption and scattering on the quantification of fluorescence diffuse optical tomography using normalized data.  JOURNAL OF BIOMEDICAL OPTICS.  17:1-9. 2012
  • Fluorescence diffuse optical tomography using the split Bregman method.  MEDICAL PHYSICS.  38:6275-6284. 2011
  • GPU-based fast iterative reconstruction of fully 3-D PET sinograms.  IEEE TRANSACTIONS ON NUCLEAR SCIENCE.  58:2257-2263. 2011
  • Split operator method for fluorescence diffuse optical tomography using anisotropic diffusion regularisation with prior anatomical information.  Biomedical Optics Express.  2:2632-2648. 2011
  • Fully 3D GPU PET reconstruction.  NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT.  648:169-171. 2011
  • Study of CT-based positron range correction in high resolution 3D PET imaging.  NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT.  648:172-175. 2011
  • Feasibility of U-curve method to select the regularization parameter for fluorescence diffuse optical tomography in phantom and small animal studies.  OPTICS EXPRESS.  19:11490-11506. 2011
  • Chronic cannabinoid administration to periadolescent rats modulates the metabolic response to acute cocaine in the adult brain.  MOLECULAR IMAGING AND BIOLOGY.  13:411-415. 2011
  • NEMA NU 4-2008 performance measurements of two commercial small-animal PET scanners: ClearPET and rPET-1.  IEEE TRANSACTIONS ON NUCLEAR SCIENCE.  58:58-65. 2011
  • A SPECT scanner for rodent imaging based on small-area gamma cameras.  IEEE TRANSACTIONS ON NUCLEAR SCIENCE.  57:2524-2531. 2010
  • Effects of the super Bialkali photocathode on the performance characteristics of a position-sensitive depth-of-interaction PET detector module.  IEEE TRANSACTIONS ON NUCLEAR SCIENCE.  57:2437-2441. 2010
  • Data acquisition electronics for gamma ray emission tomography using width-modulated leading-edge discriminators.  PHYSICS IN MEDICINE AND BIOLOGY.  55:4291-4308. 2010
  • Performance evaluation of SiPM photodetectors for PET imaging in the presence of magnetic fields.  NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT.  613:308-316. 2010

• book chapters 

  • Optical Properties of Tissues in the Near Infrared: Their Relevance for Optical Bioimaging. In: Near Infrared-Emitting Nanoparticles for Biomedical Applications.  SPRINGER. 1-20. 2020
  • Positron Emission Tomography. In: Cardiac CT, PET & MR.  Ed. John Wiley & Sons, Inc. 1-37. 2019
  • Positron Emission Tomography. In: Cardiac CT, PET & MR.  John Wiley & Sons, Inc, New York. 1-37. 2019
  • Design and Assessment Principles of Semiconductor Flat-Panel Detector-Based X-Ray Micro-CT Systems for Small-Animal Imaging. In: Integrated Microsystems: Electronics, Photonics, and Biotechnology.  CRC Press & IEEE. 309-335. 2012

• conference contributions 

  • Awake preclinical brain PET imaging based on point sources 2019
  • Tuberculosis Lesions in CT Images Inferred using 3D-CNN and Multi-Task Learning.  294-297. 2019
  • A noise correction double time-over-threshold technique for multiplexed read-outs 2018
  • Design and performance study of a quasi-spherical PET Scanner 2018
  • Design and performance study of a quasi-spherical PET scanner.  12-13. 2018
  • Design and performance study of a quasi-spherical PET scanner and hexagonal SiPM 2018
  • Diseño y estudio de un escáner PET con cobertura 4pi.  261-264. 2018
  • PDMS Microfluidic Chip for Multiplexed Testing of Antibiotics against Tuberculosis.  279-282. 2018
  • Performance evaluation of the PET subsystem of the extended FOV SuperArgus 6R preclinical scanner 2018
  • Radiomics for the Discrimination of Tuberculosis Lesions 2018
  • SiPM-based PET detector module for a 4pi span scanner 2018
  • Spectral photon-counting CT of lungs of mice infected with Mycobacterium Tuberculosis: potential for locating Tuberculosis involvement 2018
  • TOWARDS AN INFORMATIONAL MODEL FOR TUBERCULOSIS LESIONDISCRIMINATION ON X-RAY CT IMAGES.  265-268. 2018
  • Tuberculosis Histopathology on X Ray CT.  169-179. 2018
  • Accurate Lung Segmentation of Thorax CT Images on a Tuberculosis Infection Model.  251-254. 2017
  • Proposal for a PET Scanner with 4 pi Steradian Coverage.  667-670. 2017
  • 3D imaging of the cleared intact murine colon with light sheet microscopy 2016
  • Design and development of a wireless infrared EEG recorder for chicken embryos.  1-6. 2016
  • Desktop 3D printing in medicine to improve surgical navigation in acral tumors 2016
  • Geometric Calibration Workflow for High Resolution Cone Beam Micro-Computed Tomography.  1-3. 2016
  • Improving the Image Quality of High Energy Positron Based Tracers Using a Novel Tissue-Dependent, Spatially-Variant Positron Range Correction.  475-475. 2016
  • Development of a mouse lung phantom of infectious diseases for Micro-CT.  1-3. 2015
  • Evaluation of attenuation correction in a small animal PET-CT scanner.  394-397. 2015
  • Fluorescence multi-scale endoscopy and its applications in the study and diagnosis of gastro-intestinal diseases: set-up design and software implementation 2015
  • High resolution 3D microscopy of development neurogenesis in chick embryo models.  495-498. 2015
  • Highly Multiplexed DOI PET Detector Based on SiPM Sensors 2015
  • Image Quality Assessment of Multiplexed PET.  1-3. 2015
  • Simulation, Development and Testing of a PET Detector Prototype Using Monolithic Scintillator Crystals Treated with the Sub-Surface Engraving Technique.  1-3. 2015
  • A Prior-Based Image Variation (PRIVA) approach applied to motion-based compressed sensing cardiac cine MRI..  233-236. 2014
  • Dispositivo de monitorización de la señal ECG de animal de laboratorio para la adquisición de imágenes médicas con sincronismo cardio-respiratorio 2014
  • Herramienta de segmentación de pulmón y de granulomas tuberculosos en imágenes de TAC 2014
  • Implementación y validación de una herramienta de código abierto para cuantificación de estudios DSC-MRI 2014
  • In-line high resolution PET and 3T MRI hybrid device for preclinical multimodal imaging 2014
  • Iterative dual-energy material decomposition for slow kVp switching: a compressed sensing approach.  491-494. 2014
  • Novel 4D image reconstruction for dynamic X-Ray computed tomography in slow rotating scanners 2014
  • Simulations, Testing and Results for the Pixelation of LYSO Crystals for Gamma Detectors Using SSLE Techniques 2014
  • Spatially-variant positron range correction in 3D PET imaging 2014
  • Spatiotemporal total variation reconstruction for dynamic PET 2014
  • Split Bregman-singular value analysis approach to solve the compressed sensing problem of fluorescence diffuse optical tomography.  415-418. 2014
  • Tracer kinetic modeling with R for batch processing of dynamic PET studies.  301-304. 2014
  • Advanced Networked Modular Personal Dosimetry System.  1398-1401. 2013
  • Compressed sensing for cardiac MRI cine sequences: a real implementation on a small-animal scanner.  214-217. 2013
  • Evaluating the best treatment, calcium channel blocker or ketogenic diet, to reduce myocardial 18FDG uptake 2013
  • La electricidad del cuerpo humano 2013
  • Are exhausted 68Ge/68Ga generators useful in the preparation of radiopharmaceuticals for preclinical PET imaging? 2012
  • Avances tecnológicos en imagen molecular preclínica 2012
  • Brain glucose metabolism in adult rats exposed to the cannabinoid receptor agonist CP-55,940 during their adolescence 2012
  • Complete Scheme for Beam Hardening Correction in Small Animal Computed Tomography.  3835-3838. 2012
  • Diseño y caracterización de gammacámara con cristales de centelleo CsI(Na) para tomógrafo SPECT 2012
  • Dose and Scatter characteristics of a Novel Cone Beam CT System for Musculoskeletal Extremities 2012
  • Effects of morphine self-administration on glucose brain metabolism of adults rats that were exposed during their adolescence to the cannabinoid receptor agonist CP-55,940 2012
  • Generadores de 68GE/68GA"agotados": utilidad en la preparación automática de 68GA DOTATOC para investigación en pequeño animal 2012
  • Herramienta automática para calibrado geométrico de un tomógrafo SPECT de animales de laboratorio 2012
  • Investigation of Different Compressed Sensing Approaches for Respiratory Gating in Small Animal CT.  3344-3346. 2012
  • Iterative Dual-Energy Raw Data Decomposition for Slow kVp Switching: a Feasibility Study.  473. 2012
  • MRI compatibility of PS-PMT DOI PET detectors modules for in-line multimodality preclinical studies 2012
  • Un nuevo algoritmo para la reducción del artefacto de anillo en tomografía computarizada de pequeño animal 2012
  • jClustering, un entorno de código libre para ImageJ para el desarrollo de algoritmos de clustering aplicados a segmentación de imágenes médicas dinámicas 2012
  • ART with Split Bregman Denoising: A Reconstruction Method for Fluorescence Diffuse Optical Tomography 2011
  • Assessment of New Photosensors for Fast Timing Applications with Large Scintillator Detectors.  72-74. 2011
  • Automatic Cardiac Gating of Small-animal PET from List-mode Data.  206-209. 2011
  • Automatic Monte-Carlo Based Scatter correction for X-ray Cone Beam CT using General Purpose Graphic Processing Units (GP-GPU): a Feasibility study.  3705-3709. 2011
  • Automatic Self Gating of Small-Animal PET from List-Mode Data 2011
  • Clustering leader-follower para la segmentación automática de estudios PET cardiacos 2011
  • Corrección empírica de primer y segundo orden del artefacto de endurecimiento de haz en imágenes de micro-TAC.  433-436. 2011
  • Deadtime and pile-up correction method based on the singles to coincidences ratio for PET.  2933-2935. 2011
  • Design of DOI PET detector Modules using phoswich and SIPMs: First Results.  3311-3313. 2011
  • Equipos para experimentación animal 2011
  • FBP Reconstruction of Sinograms with Gaps Based on the Inversion of a Perturbed Matrix 2011
  • Fully-3D GPU PET Reconstruction.  169-171. 2011
  • Herramienta para la segmentación de estructuras óseas de embriones de ave in ovo en imágenes de CT.  721-724. 2011
  • High-Resolution Dynamic Cardiac MRI on Small Animals Using Reconstruction Based on Split Bregman Methodology.  3462-3464. 2011
  • Interfaz de usuario para la adquisición de datos, calibración y reconstrucción de imagen para tomógrafo SPECT de animales de laboratorio.  515-518. 2011
  • Kinetic Modeling 2011
  • Leader-follower clustering algorithm for automatic segmentation of cardiac PET studies.  3133-3136. 2011
  • Measurement of activity Produced by Low energy Pronton Beam in metals using off-Line PET Imaging.  3514-3517. 2011
  • Molecular imaging of pheochromocytoma with 68Ga-DOTATOC-PET: Comparative pilot study with neuropancreatic tumor 2011
  • Monte Carlo Simulation of a TOF-PET Scanner.  4420-4428. 2011
  • PET and SPECT imaging 2011
  • PeneloPET simulations of the Biograph ToF clinical PET scanner.  4420-4428. 2011
  • Quantification Limits of Iterative PET Reconstruction Algorithms and Improved Estimation of Kinetic Constants.  2968-2972. 2011
  • Quantification limits of iterative PET reconstruction algorithms and improved estimation of kinetic constants.  1766-1770. 2011
  • Reconstrucción de Tomografía Óptica Difusiva por Fluorescencia usando Compressed Sensing Split Bregman.  599-602. 2011
  • Skull deformation patterns in two mouse genetic syndromes, Costello and CFC, using computed tomography 2011
  • Uso del método de Split Bregman para la resolución del problema de compressed sensing en imagen de resonancia magnética dinámica cardiaca para pequeño animal.  453-456. 2011
  • A Statistical Image Reconstruction Algorithm for Polyenergetic X-Ray CT: Preliminary Results on a Small Animal Scanner 2010
  • Aceleración de un Programa de Reconstrucción Iterativa para PET mediante el uso de GPUs 2010
  • Corrección de atenuación de imágenes PET usando datos de TAC en el escáner para animales pequeños Argus PET/CT 2010
  • Cuantificación del infarto de miocardio en imágenes PET mediante mapas polares.  1-4. 2010
  • Iterative Automatic Segmentation in Cardiac PET Based on TAC Correlation: Preliminary Results 2010
  • Performance Evaluation of SiPM Photodetectors for PET Imaging in the Presence of Magnetic Fields 2010
  • Segmentación automática de estudios PET cardíacos con 13NH3 basada en correlación iterativa 2010
  • Validation of peneloPET simulations of the Biograph PET/CT scanner with TOF capabilities 2010
  • Viabilidad del uso de fotodetectores SiPM en sistemas PET/IRM 2010
  • Evaluación multimodal del infarto de miocardio crónico en ratas: comparación entre RM y PET 2009
  • Performance Evaluation of SiPM Photosensors in the Presence of Magnetic Fields.  171-172. 2009
  • Performance evaluation of SIPM photosensors for PET imaging in the presence of magnetic fields.  163. 2009
  • Performance Evaluation of SiPM Detectors for PET Imaging in the Presence of Magnetic Fields.  3591-3595. 2008