Massively parallelizable list-mode reconstruction using a Monte Carlo-based elliptical Gaussian model Articles uri icon

publication date

  • January 2013

start page

  • 1

end page

  • 11

issue

  • 1 (012504)

volume

  • 40

International Standard Serial Number (ISSN)

  • 0094-2405

Electronic International Standard Serial Number (EISSN)

  • 2473-4209

abstract

  • Purpose: A fully three-dimensional (3D) massively parallelizable list-mode ordered-subsets expectation-maximization (LM-OSEM) reconstruction algorithm has been developed for high-resolution PET cameras. System response probabilities are calculated online from a set of parameters derived from Monte Carlo simulations. The shape of a system response for a given line of response (LOR) has been shown to be asymmetrical around the LOR. This work has been focused on the development of efficient region-search techniques to sample the system response probabilities, which are suitable for asymmetric kernel models, including elliptical Gaussian models that allow for high accuracy and high parallelization efficiency. The novel region-search scheme using variable kernel models is applied in the proposed PET reconstruction algorithm...

subjects

  • Biology and Biomedicine
  • Medicine

keywords

  • list-mode reconstruction; pet; kernel model; gpu reconstruction