- PLoS One Journal
- September 2014
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International Standard Serial Number (ISSN)
- Besides its application in oncology, 18F-FDG PET-CT imaging is also useful in the diagnosis of certain lung infections, inflammatory diseases, and atherosclerotic plaques. Myocardial uptake of 18F-FDG may hamper visualization of the lesions caused by these diseases. Two approaches have been proposed for reducing myocardial uptake in preclinical studies, namely, calcium channel blockers (verapamil) and high-fat diets such as commercial ketogenic diets and sunflower seed diets. The objective of this study was to compare the efficacy of these approaches in reducing myocardial uptake of 18F-FDG in mice.
- oncology; 18f-fdg pet-ct; lung infections; inflammatory diseases; atherosclerotic plaques; myocardial uptake; calcium channel blockers; verapamil; high-fat diet; ketogenic diet; sunflower seed diet