This work analyzes the sensitivity to neutrons of SIMD (Single Instruction Multiple Data) microprocessor extensions. To this purpose, the ARM SIMD coprocessor (NEON™) was selected as a case study and neutron radiation experiments were performed on a commercial device running NEON software. In addition, we analyze the benefits of using the NEON coprocessor as a means to efficiently implement data-flow hardening approaches. Experimental results show that SIMD extensions have a great potential to improve performance and reduce the overheads associated to software data-flow hardening.