- BMC BIOINFORMATICS Journal
- May 2010
- Suppl 5
Digital Object Identifier (DOI)
International Standard Serial Number (ISSN)
A drug-drug interaction (DDI) occurs when one drug influences the level or activity of another drug. The detection of drug interactions is an important research area in patient safety since these interactions can become very dangerous and increase
health care costs. Although there are different databases supporting health care professionals
in the detection of drug interactions, this kind of resources is rarely complete.
Drug interactions are frequently reported in journals of clinical pharmacology, making
medical literature the most effective source for the detection of drug interactions.
However, the increasing volume of the literature overwhelms health care professionals
trying to keep an up-to-date collection of all reported DDIs. The development of automatic
methods for collecting, maintaining and interpreting this information is crucial for
achieving a real improvement in their early detection. Information Extraction (IE)
techniques can provide an interesting way of reducing the time spent by health care
professionals on reviewing the literature. Nevertheless, no approach has been carried
out to extract drug-drug interactions from biomedical texts.