MLCARE - Machine Learning Computational Advancements for peRsonalized mEdicine Projects uri icon

type

  • European Research Project

reference

  • 101226456

date/time interval

  • January 1, 2026 - December 31, 2029

abstract

  • Personalized medicine represents a paradigm shift in healthcare, transitioning from generalized treatment strategies to highly personalized
    care. This transformation is driven by rapid advancements in digital technologies, which generate massive volumes of data from diverse
    sources, including genomic sequences, high-resolution imaging, wearable devices, and electronic health records (EHRs). However,
    despite an annual estimate of 50 petabytes of data generated per hospital, only a fraction is utilized effectively. Harnessing this untapped
    potential offers a transformative opportunity to uncover novel disease mechanisms and deliver more precise and effective therapeutic
    interventions. The MLCARE project seeks to revolutionize personalized medicine by developing cutting-edge AI solutions that integrate
    genomic, clinical, and environmental data into holistic, multimodal patient representations. Through innovative approaches such as

    Foundation Models and advanced generative AI methods, MLCARE will address critical challenges in processing complex, high-
    dimensional, and multimodal datasets. Emphasis will be placed on ensuring the trustworthiness, explainability, and security of AI

    applications to support real-world clinical decision-making. A core mission of MLCARE is to train a new generation of interdisciplinary
    researchers with expertise spanning AI, computational biology, and healthcare. The program will equip doctoral candidates with the
    technical, analytical, and ethical skills needed to lead the future of patient-centered, AI-driven medicine. By combining state-of-the-art
    research with a comprehensive training program, MLCARE aims to set new standards in personalized healthcare, ensuring equitable,
    data-driven solutions that improve outcomes across diverse populations. This project is poised to position Europe at the forefront of
    global innovation in precision medicine, delivering a timely and impactful response to evolving healthcare challenges.