Sol-gel synthesis of Mg(OH)(2) and Ca(OH)(2) nanoparticles: a comparative study of their antifungal activity in partially quaternized p(DMAEMA) nanocomposite films Articles uri icon

authors

  • SIERRA FERNANDEZ, A.
  • DE LA ROSA GARCIA, S. C
  • YANEZ MACIAS, R.
  • GUERRERO SANCHEZ, C.
  • GOMEZ VILLALBA, L. S.
  • GĂ“MEZ CORNELIO, S.
  • RABANAL JIMENEZ, MARIA EUGENIA
  • SCHUBERT, U. S
  • FORT, R.
  • QUINTANA, P.

publication date

  • January 2019

start page

  • 310

end page

  • 321

issue

  • 1

volume

  • 89

International Standard Serial Number (ISSN)

  • 0928-0707

abstract

  • The evaluation of the antifungal activity of Mg(OH)(2) and Ca(OH)(2) nanoparticles (NPs), synthesized by sol-gel method and their mixtures at different concentrations, is reported. The antifungal activity of the hydroxide NPs was studied using Aspergillus niger and Penicillium oxalicum isolated from stone surfaces. These model organisms were selected due to their ability to grow on outdoor and indoor climates and their significant impact on human health. Moreover, the antifungal activity of Mg(OH)(2) and Ca(OH)(2) NPs dispersed in positively charged polymeric matrices based on partially quaternized poly(2-(dimethylamino ethyl) methacrylate) (pDMAEMA) was studied. With respect to the morphology, particle size, and textural properties of the NPs, the mixtures of Mg-Ca hydroxides revealed a uniform and smaller particle size, along with a greater surface area, as compared to pristine Ca(OH)(2) NPs. However, the Ca(OH)(2) and a mixture of Mg(OH)(2) and Ca(OH)(2) (10:90 weight ratio) NPs, showed an enhanced growth inhibition of A. niger and P. oxalicum, suggesting that the effect of particle size on the antifungal activity would not be a preponderating factor. In addition, improved antifungal properties against A. niger and P. oxalicum were detected in composite coatings based on hydroxide NPs dispersed in quaternized p(DMAEMA-co-METAI). The use of these systems might provide promising composite materials with potential antifungal properties for various applications. [GRAPHICS] HighlightsPure Mg(OH)(2), Ca(OH)(2), and mixtures of both NPs were successfully synthesized by sol-gel method.The mixtures based on Mg-Ca hydroxides showed a uniform and smaller particle size, along with a greater surface area.The effect of particle size on the antifungal activity would not be a preponderating factor.The Ca(OH)(2) and Mg(OH)(2):Ca(OH)(2) (10:90wt%) NPs had an enhanced antifungal efficiency.The use of Mg(OH)(2) and Ca(OH)(2) NPs in p(DMAEMA-co-METAI) composites improved the anti

keywords

  • aspergillus niger; penicillium oxalicum; hydroxide nanoparticles; antifungal coatings; poly[(2-dimethylamino) ethyl methacrylate]; antimicrobial activity; oxide nanoparticles; antibacterial; hydroxide; zno; inhibition; protection; mechanism; limestone; property