Triethylphosphite as a network forming agent enhances in vitro biocompatibility and corrosion protection of hybrid organic-inorganic sol-gel coatings for Ti6Al4V alloys Articles uri icon

authors

  • El Hadad, Amir Abdelsami
  • BARRANCO, VIOLETA
  • JIMENEZ MORALES, ANTONIA
  • HICKMAN, G. J.
  • GALVAN SIERRA, JUAN CARLOS
  • PERRY, C. C.

publication date

  • October 2014

start page

  • 7955

end page

  • 7963

issue

  • 45

volume

  • 2

International Standard Serial Number (ISSN)

  • 2050-750X

Electronic International Standard Serial Number (EISSN)

  • 2050-7518

abstract

  • The biocompatibility and life of metallic implants can be enhanced through improving the biocompatibility and corrosion protection characteristics of the coatings used with these materials. In this study, triethylphosphite (TEP) was used to introduce phosphorus into organic-inorganic hybrid silica based sol-gel coatings prepared using gamma-methacryloxypropyltrimethoxysilane and tetramethylorthosilicate. Addition of TEP dramatically increased the rate of intermolecular condensation and resulted in materials showing greater cross-linking. Protein (fibrinogen) uptake, osteoblast in vitro biocompatibility and corrosion resistance was enhanced in coatings containing TEP. Although higher concentrations of phosphorus supported the greatest improvement in biocompatibility, a compromise in the phosphorus concentration used would be required if corrosion resistance was most desirable parameter for optimisation. Films prepared by dip coating on Ti6Al4V alloys from these sols offer a promising alternative to wholly metallic prostheses.

keywords

  • gamma-methacryloxypropyltrimethoxysilane; magnesium; ti-6al-4v; behavior; surface; films; bone; dissolution; hydrolysis; diagrams