Enhancing in vitro biocompatibility and corrosion protection of organic-inorganic hybrid sol-gel films with nanocrystalline hydroxyapatite Articles uri icon

authors

  • El Hadad, Amir Abdelsami
  • BARRANCO, VIOLETA
  • JIMENEZ MORALES, ANTONIA
  • PEÓN, E
  • HICKMAN, G. J.
  • PERRY, C. C.
  • GALVAN SIERRA, JUAN CARLOS

publication date

  • June 2014

start page

  • 3886

end page

  • 3896

issue

  • 24

volume

  • 2

International Standard Serial Number (ISSN)

  • 2050-750X

Electronic International Standard Serial Number (EISSN)

  • 2050-7518

abstract

  • Application of novel organic-inorganic hybrid sol-gel coatings containing dispersed hydroxyapatite (HAp) particles improves the biocompatibility, normal human osteoblast (NHOst) response in terms of osteoblast viability and adhesion of a Ti6Al4V alloy routinely used in medical implants. The incorporation of HAp particles additionally results in more effective barrier proprieties and improved corrosion protection of the Ti6Al4V alloy through higher degree of cross-linking in the organopolysiloxane matrix and enhanced film thickness. This journal is © the Partner Organisations 2014.

keywords

  • biocompatibility; corrosion protection; hydroxyapatite; inorganic coatings; degree of cross-linking; hydroxyapatite (hap); medical implants; nanocrystallines; normal human osteoblasts; organic-inorganic hybrid; organic-inorganic hybrid sol-gel coatings; organopolysiloxanes; sol-gels