Recovering fluorophore location and orientation from lifetimes Articles uri icon

publication date

  • January 2013

start page

  • 421

end page

  • 430

issue

  • 1

volume

  • 21

International Standard Serial Number (ISSN)

  • 1094-4087

abstract

  • In this paper, we study the possibility of using lifetime data to estimate the position and orientation of a fluorescent dipole source within a disordered medium. The vector Foldy-Lax equations are employed to calculate the interaction between the fluorescent source and the scatterers that are modeled as point-scatterers. The numerical experiments demonstrate that if good prior knowledge about the positions of the scatterers is available, the position and orientation of the dipole source can be retrieved from its lifetime data with precision. If there is uncertainty about the positions of the scatterers, the dipole source position can be estimated within the same level of uncertainty.

keywords

  • disordered media; scatterers