The feasibility of fabricating high-density ports from Inconel 718 powder using three-dimensional printing (3DP) was assessed. Parts were subsequently hot isostatically pressed (HIPed) to achieve full density. After optimization of the particle-size distribution, parts were fabricated by means of the 3D-printing process utilizing two different devices in order to examine the influence of the binder. Printed parts were sintered in high vacuum at 1,563K (1,290°C) or 1,573K (1,300°C) and charactertzed in terms of density and microstructure. Finally, sintered parts were HIPed at 1,473K (1,200°C) and 142 MPa, followed by a second HIPing cycle at 1,483K (1,210°C) and 206 MPa for 3 h in argon to achieve full density.