abbreviation
- J MED CHEM
JOURNAL OF MEDICINAL CHEMISTRY
Journal
Overview
publication venue for
- Lead optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series for the treatment of malaria. 63. 2020
- Benzothiazole-Based LRRK2 Inhibitors as Wnt Enhancers and Promoters of Oligodendrocytic Fate. 63:2638-2655. 2020
- Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis. 62. 2019
- Identification of Fast-Acting 2,6-Disubstituted Imidazopyridines That Are Efficacious in the in Vivo Humanized Plasmodium falciparum NODscidIL2R?null Mouse Model of Malaria. 61:4213-4227. 2018
- Synthesis and Structure&-Activity Relationships of the Novel Antimalarials 5-Pyridinyl-4(1H)-Pyridones. 61:3422-3435. 2018
- Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3ß and Tau-Aggregation Inhibitors. 61:7640-7656. 2018
- The Discovery of Novel Antimalarial Aminoxadiazoles as a Promising Nonendoperoxide Scaffold. 60:6880-6896. 2017
- Identification of a Potential Antimalarial Drug Candidate from a Series of 2-Aminopyrazines by Optimization of Aqueous Solubility and Potency across the Parasite Life Cycle. 59:9890-9905. 2016
- Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials. 59:6101-6120. 2016
- Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial Activity. 59. 2016
- A novel pyrazolopyridine with in vivo activity in Plasmodium berghei- and Plasmodium falciparum-infected mouse models from structure-activity relationship studies around the core of recently identified antimalarial imidazopyridazines. 58:8713-8722. 2015
- N-aryl-2-aminobenzimidazoles: Novel, efficacious, antimalarial lead compounds. 57. 2014
- Aminoazabenzimidazoles, a Novel Class of Orally Active Antimalarial Agents. 57:5702-5713. 2014
- Encoded library technology as a source of hits for the discovery and lead optimization of a potent and selective class of bactericidal direct inhibitors of mycobacterium tuberculosis InhA. 57:1276-1288. 2014
- Structure-guided lead optimization of triazolopyrimidine-ring substituents identifies potent plasmodium falciparum dihydroorotate dehydrogenase inhibitors with clinical candidate potential. 54:5540-5561. 2011
International Standard Serial Number (ISSN)
- 0022-2623
Electronic International Standard Serial Number (EISSN)
- 1520-4804