Temperature management in acute brain injury: A narrative review=Control térmico en el daño cerebral agudo: revisión narrativa Articles uri icon

authors

  • TEJERINA ALVAREZ, EVA ESTHER
  • LORENTE BALANZA, JOSE ANGEL

publication date

  • June 2024

start page

  • 341

end page

  • 355

issue

  • 6

volume

  • 48

International Standard Serial Number (ISSN)

  • 0210-5691

Electronic International Standard Serial Number (EISSN)

  • 1578-6749

abstract

  • Temperature management has been used in patients with acute brain injury resulting from different conditions, such as post-cardiac arrest hypoxic-ischaemic insult, acute ischaemic stroke, and severe traumatic brain injury. However, current evidence offers inconsistent and often contradictory results regarding the clinical benefit of this therapeutic strategy on mortality and functional outcomes. Current guidelines have focused mainly on active prevention and treatment of fever, while therapeutic hypothermia (TH) has fallen into disuse, although doubts persist as to its effectiveness according to the method of application and appropriate patient selection. This narrative review presents the most relevant clinical evidence on the effects of TH in patients with acute neurological damage, and the pathophysiological concepts supporting its use.

subjects

  • Biology and Biomedicine