A comprehensive framework has been developed to apply the monomiality principle from mathematical physics to various mathematical concepts from special functions. This paper presents research on a novel family of multivariate Hermite polynomials associated with Apostol-type Frobenius¿Euler polynomials. The study derives the generating expression, operational rule, differential equation, and other defining characteristics for these polynomials. Additionally, the monomiality principle for these polynomials is verified. Moreover, the research establishes series representations, summation formulae, and operational and symmetric identities, as well as recurrence relations satisfied by these polynomials.