Synthesis, Characterization and In Vitro Cytotoxic Effects of Cu:Co3O4 Nanoparticles Via Microwave Combustion Method Articles uri icon

authors

  • Sundararajan, M.
  • Subramani, A.
  • Ubaidullah, Mohd
  • Shaikh, Shoyebmohamad F.
  • PANDIT, BIDHAN
  • Jesudoss, S. K.
  • Kamalakannan, M.
  • Yuvaraj, S.
  • Subudhi, Partha Sarathi
  • Dash, Chandra Sekhar

publication date

  • July 2022

start page

  • 1821

end page

  • 1830

issue

  • 4

volume

  • 33

International Standard Serial Number (ISSN)

  • 1040-7278

Electronic International Standard Serial Number (EISSN)

  • 1572-8862

abstract

  • Utilizing microwave combustion method Co3-xCuxO4 (x = 0 and 0.5) nanoparticles were prepared utilizing l-alanine as fuel. The phase and crystal structure of Co3O4 and Cu: Co3O4 nanoparticles are studied employing X-ray diffraction technique, which further ensured the phase formation and crystallite size was determined. The crystallite size was observed to be 27.39 and 39.22 nm respectively for pure and Cu:Co3O4 nanoparticles respectively. HRSEM images of the prepared samples unveiled spherical morphology. The presence of Cu, Co and O is observed through Energy dispersive X-ray spectra. Optical bandgap values were assessed and they were observed to lie within 2.87–2.97 eV. FT-IR spectra peaks at 573 and 664 cm−1 were responsible for Co3+ of octahedral sites besides Co2+ of tetrahedral sites respectively. The M-H loops exhibited super paramagnetic behaviour. Furthermore, we have investigated the various concentrations of Co1-xCuxO (x = 0 and 0.5) nanoparticles towards potential cytotoxicity effect against the A549 human lung epithelial cancer cell lines.

subjects

  • Chemistry
  • Industrial Engineering
  • Materials science and engineering

keywords

  • a549; apoptosis; band gap; cu-co3o4 nanoparticles; magnetization and vibrational spectra; mtt