Energy-efficient transformations of national economies constitutes a mechanism that will facilitate the creation of an effective national social reproduction system. This paper investigates the national economic structure of Ukraine to determine the level of eco-destructive impacts caused by human and industrial activities at the following four levels: low, average, high and critical. Environmental risk assessment was the methodology adopted for evaluating the impacts of different kinds of economic activities in Ukraine. Three indicators used for determining the impact of eco-destructive activities are environmental costs, environmental cost intensity, and environmental risk. Using Sumy States as a case study, the investigation evaluated relevant ecological and economic indicators and determined the average annual environmental costs of production in Ukraine.