Antibacterial Strategies from the Sea: Polymer-Bound Cl-Catechols for Prevention of Biofilm Formation Articles uri icon

authors

  • García-Fernández, Luis
  • Cui, Jiaxi
  • Serrano, Cristina
  • Shafiq, Zahid
  • Gropeanu, Radu A.
  • SAN MIGUEL ARNANZ, VERONICA
  • Iturri Ramos, Jagoba
  • Wang, Miao
  • Auernhammer, Gunther K.
  • Ritz, Sandra
  • Golriz, Ali A.
  • BERGER, RÜDIGER
  • Wagner, Manfred
  • del Campo, Aránzazu

publication date

  • November 2012

start page

  • 529

end page

  • 533

issue

  • 4

volume

  • 25

International Standard Serial Number (ISSN)

  • 0935-9648

Electronic International Standard Serial Number (EISSN)

  • 1521-4095

abstract

  • Inspired by the amino acid 2-chloro-4,5-dihydroxyphenylalanine (Cl-DOPA), present in the composition of the proteinaceous glue of the sandcastle worm Phragmatopoma californica, a simple strategy is presented to confer antifouling properties to polymer surfaces using (but not releasing) a bioinspired biocide. Cl-Dopamine is used to functionalize polymer materials and hydrogel films easily, to prevent biofilm formation on them.

keywords

  • biomimetics; catechols; antibacterial strategies; dopa