In-vivo, non-invasive detection of hyperglycemic states in animal models using mm-wave spectroscopy Articles uri icon

publication date

  • September 2016

start page

  • 1

end page

  • 8

issue

  • 34035

volume

  • 6

International Standard Serial Number (ISSN)

  • 2045-2322

abstract

  • Chronic or sustained hyperglycemia associated to diabetes mellitus leads to many medical complications, thus, it is necessary to track the evolution of patients for providing the adequate management of the disease that is required for the restoration of the carbohydrate metabolism to a normal state. In this paper, a novel monitoring approach based on mm-wave spectroscopy is comprehensively described and experimentally validated using living animal models as target. The measurement method has proved the possibility of non-invasive, in-vivo, detection of hyperglycemia associated conditions in different mouse models, making possible to clearly differentiate between several hyperglycemic states.

keywords

  • diabetic complications; glycated albumin; hemoglobin; mellitus