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This study describes the microstructures of an ODS/Fe12Cr alloy before and after Fe+ irradiation at 500 degrees C to a dose of 2.5 dpa and compares these microstructures with those of a reference Fe12Cr alloy produced following the same pulvimetallurgical route. The grain and dislocation structures of the alloys did not seem to change after irradiation. The main difference after irradiation was the appearance of small loops, which had similar sizes, distribution and densities in the ODS and reference alloys. The size distributions and chemical compositions of the ODS particles were similar to those found before irradiation.